LDLR antibody (AA 499-511)

Catalog No. ABIN1909537

This Rabbit Polyclonal antibody specifically detects LDLR in WB, IHC, ICC and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for LDLR antibody (AA 499-511) (ABIN1909537)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDLR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LDLR Antibody

Binding Specificity: AA 499-511

Brand: IHC-plus™

Specificity: Synthetic peptide from murine LDL receptor amino acids 499-511 (SVADTKGVKRRTL)

Purification: Affinity purified

Immunogen: Synthetic peptide from mouse LDL receptor amino acids 499-511 (SVADTKGVKRRTL). Percent identity by BLAST analysis: Mouse (100%), Human, Gibbon, Monkey, Rat, Bovine, Panda, Pig (92%), Marmoset, Dog, Bat, Hamster, Elephant, Horse, Platypus (85%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ICC, IHC, IHC-P (10 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Reconstitute with 0.5 mL of deionized water

Concentration: Lot specific

Buffer: TBS,  pH 7.4, containing 50 % glycerol, 0.1 % BSA, and 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDLR / LDL Receptor

Background: Name/Gene ID: LDLR

Synonyms: LDLR, FHC, LDL receptor, LDLCQ2

Gene ID: 3949

Pathways: Hepatitis C, Lipid Metabolism