NGFR antibody (C-Term)

Catalog No. ABIN1917233

The Rabbit Polyclonal anti-NGFR antibody has been validated for WB, IHC, IHC (p), ICC and IHC (fro). It is suitable to detect NGFR in samples from Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Hamster and Bat. There are 2+ publications available.

Quick Overview for NGFR antibody (C-Term) (ABIN1917233)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Hamster, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NGFR Antibody

Binding Specificity: AA 407-425, C-Term

Specificity: Species cross-reactivity: Rat. Expected to cross-react with Human (94 % identity with immunogen) and Mouse (100 % identity with immunogen) due to sequence homology.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide: K-QRADIVESLCSESTATSPV conjugated to KLH, corresponding to amino acids 407-425 of Rat NGFR p75 with N-terminally added lysine.

Type of Immunogen: Synthetic peptide - KLH conjugated

Isotype: IgG

Application Details

Application Notes: Approved: ICC, IHC, IHC-Fr, IHC-P (5 μg/mL), WB (1:5000)

Usage: Suitable for use in Western Blot, Immunohistochemistry (Frozen and Paraffin) and Immunocytochemistry.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01 M PBS,  pH 7.4, 1 % BSA, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

References for anti-NGFR antibody (ABIN1917233)

Kendall, Ekman, Skiöldebrand: "Nerve growth factor receptors in equine synovial membranes vary with osteoarthritic disease severity." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2022) (PubMed).

Kendall, Nyström, Ekman, Hultén, Lindahl, Hansson, Skiöldebrand: "Nerve growth factor in the equine joint." in: Veterinary journal (London, England : 1997), Vol. 267, pp. 105579, (2021) (PubMed).

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Alternative Name: NGFR / CD271 / p75

Background: Name/Gene ID: NGFR
Family: TNF Receptor

Synonyms: NGFR, CD271, CD271 antigen, gp80-LNGFR, Nerve growth factor receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, NGF receptor, TNFRSF16

Gene ID: 4804

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding