SQSTM1 antibody (AA 375-425)

Catalog No. ABIN1920949

This Rabbit Polyclonal antibody specifically detects SQSTM1 in WB, IHC, IF, IP and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Sheep, Chicken and Xenopus laevis.

Quick Overview for SQSTM1 antibody (AA 375-425) (ABIN1920949)

Target: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivity: Human, Mouse, Rat, Sheep, Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SQSTM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SQSTM1 Antibody

Binding Specificity: AA 375-425

Specificity: Region between residue 375 and 425 of human Sequestosome-1 using the numbering given in entry NP_003891.1 (GeneID 8878).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:250 - 1:1000), IHC, IHC-P (1:500 - 1:2000), IP (2 - 5 μg/mg lysate), WB (1:2000 - 1:10000)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Lung Adenocarcinoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for SQSTM1

Target: SQSTM1 (Sequestosome 1 (SQSTM1))

Alternative Name: p62 / SQSTM1

Background: Name/Gene ID: SQSTM1

Synonyms: SQSTM1, A170, ORCA, OSIL, Paget disease of bone 3, p60, p62, PDB3, Sequestosome-1, Ubiquitin-binding protein p62, Oxidative stress induced like, p62B, ZIP3, Sequestosome 1, EBI3-associated protein p60, EBIAP

Gene ID: 8878

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy