BRCA1 antibody (pSer1280)

Catalog No. ABIN1959495

The Rabbit Polyclonal anti-BRCA1 antibody (ABIN1959495) specifically detects BRCA1 in WB, IP and PLA. The antibody is reactive with Human and Monkey samples.

Quick Overview for BRCA1 antibody (pSer1280) (ABIN1959495)

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Proximity Ligation Assay (PLA)

Product Details anti-BRCA1 Antibody

Binding Specificity: pSer1280

Specificity: Human BRCA1 (phospho-Ser1280)

Purification: Immunoaffinity purified

Immunogen: Phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1280 according to the numbering given in entry NP_009225.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (2 μg/mg lysate), PLA (1:1000 - 1:10000), WB (1:1000 - 1:10000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: BRCA1

Background: Name/Gene ID: BRCA1

Synonyms: BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS

Gene ID: 672

NCBI Accession: NP_009225

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus