BRCA1 antibody (pSer1524)

Catalog No. ABIN1959508

This Rabbit Polyclonal antibody specifically detects BRCA1 in WB, IP and PLA. It exhibits reactivity toward Human.

Quick Overview for BRCA1 antibody (pSer1524) (ABIN1959508)

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Proximity Ligation Assay (PLA)

Product Details anti-BRCA1 Antibody

Binding Specificity: pSer1524

Specificity: Human BRCA1 (phospho-Ser1524)

Purification: Immunoaffinity purified

Immunogen: Phosphorylated synthetic peptide, which represented a portion of human Breast Cancer Gene 1 (GeneID 672) around serine 1524 according to the numbering given in entry NP_009225.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IP (2 μg/mg lysate), PLA (1:1000 - 1:10000), WB (1:500 - 1:5000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: BRCA1

Background: Name/Gene ID: BRCA1

Synonyms: BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS

Gene ID: 672

NCBI Accession: NP_009225

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus