MCM2 antibody (pSer53)

Catalog No. ABIN1959607

This Rabbit Polyclonal antibody specifically detects MCM2 in WB, IHC, IF, IHC (p) and PLA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MCM2 antibody (pSer53) (ABIN1959607)

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)

Product Details anti-MCM2 Antibody

Binding Specificity: pSer53

Specificity: Human MCM2 (phospho-Ser53)

Purification: Immunoaffinity purified

Immunogen: Phosphorylated synthetic peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 53 according to the numbering given in entry NP_004517.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:50 - 1:250), IHC, IHC-P (1:100 - 1:500), PLA (1:200 - 1:4000), WB (1:1000 - 1:2500)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Cancer, Ovarian.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for MCM2

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Alternative Name: MCM2

Background: Name/Gene ID: MCM2

Synonyms: MCM2, BM28, Cell devision cycle-like 1, D3S3194, Cdc19, Cyclin-like 1, KIAA0030, Nuclear protein BM28, CDCL1, MITOTIN

Gene ID: 4171

NCBI Accession: NP_004517

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA