CD11b antibody

Catalog No. ABIN1959978

This anti-CD11b antibody is a Mouse Monoclonal antibody detecting CD11b in FACS, IHC, IP, IHC (fro), ICC, Func, BR and Neut. Suitable for Human and Primate.

Quick Overview for CD11b antibody (ABIN1959978)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Clone: ICRF44

Product Details anti-CD11b Antibody

Specificity: Monoclonal antibody ICRF44 recognizes CD11b (Mac-1alpha), a 165-170 kD type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells.

Purification: Protein A purified

Immunogen: Rheumatoid synovial cells and human monocytes.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Flo, Func, ICC, IHC, IHC-Fr, IP, Neut

Usage: Functional Application: blocking of granulocyte activation.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: ITGAM / CD11b

Background: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gene ID: 3684

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation