Glutamate Receptor 1 antibody (AA 847-851)

Catalog No. ABIN197513

This Rabbit Polyclonal antibody specifically detects Glutamate Receptor 1 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Glutamate Receptor 1 antibody (AA 847-851) (ABIN197513)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: AA 847-851

Specificity: This Antibody detects endogenous levels of total GluR1 protein.

Purification: Affinity-Chromatography using epitope-specific immunogen.

Immunogen: Peptide Sequenece around amino acids 847~851 (Q-Q-SP-I-N) derived from Human GluR1.

Application Details

Application Notes: Western Blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: Glutamate Receptor 1 / GLUR1

Background: Glutamate receptor 1 (AMPA) belongs to the glutamate-gated ion channel and binds AMPA, glutamate and kainate. L-Glutamate is the major excitatory neurotransmitter in the mammalian CNS, acting through both ligand gated ion channels (ionotropic receptors, composed of subunits GluR1-4) and G-protein coupled (metabotropic) receptors. The AMPA glutamate receptors mediate fast synaptic transmission in the CNS.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gene ID: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signaling