HMGCR antibody (AA 588-887) (FITC)

Catalog No. ABIN1991061

The FITC-conjugated Rabbit Polyclonal anti-HMGCR antibody (ABIN1991061) specifically detects HMGCR in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for HMGCR antibody (AA 588-887) (FITC) (ABIN1991061)

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCR antibody is conjugated to FITC

Application: Western Blotting (WB), ELISA

Product Details anti-HMGCR Antibody (FITC)

Binding Specificity: AA 588-887

Purpose: HMGCR Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: HMGCR

Background:

Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Aliases: 3 hydroxy 3 methylglutaryl CoA reductase antibody, 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody, 3 hydroxymethylglutaryl CoA reductase antibody, 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody, 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody, 3H3M antibody, HMDH_HUMAN antibody, HMG CoA reductase antibody, HMG CoAR antibody, HMG-CoA reductase antibody, Hmgcr antibody, Hydroxymethylglutaryl CoA reductase antibody, LDLCQ3 antibody, MGC103269 antibody, Red antibody

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha