APP antibody (N-Term)

Catalog No. ABIN200259

This anti-APP antibody is a Mouse Monoclonal antibody detecting APP in WB, ELISA, IHC, IHC (p) and IHC (fro). Suitable for Human.

Quick Overview for APP antibody (N-Term) (ABIN200259)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-APP Antibody

Binding Specificity: N-Term

Specificity: Recognizes human b-amyloid precursor protein (b-APP695) that has a predicted amino acid sequence length of 695. There are 3 known b-APP proteins (b APP695, b APP751, b APP770) thought to be the source of amyloid b-peptide. Recognizes an epitope within the first 200 amino acids in the b-APP amino terminus This antibody will react with all 3 forms.

Purification: Purified

Immunogen: Rec b-APP695.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA (0.1 - 0.5 μg/mL), IHC, IHC-Fr, IHC-P, WB (0.5 - 1 μg/mL)

Usage: Suitable for use in Immunohistochemistry, Western Blot and ELISA. Immunohistochemistry (Paraffin-embedded tissues): 5-10 μg/mL. Suitable for immunohistochemical staining of alcohol-fixed paraffin-embedded or frozen tissue sections. Other fixatives may also work following formic acid treatment. Western Blot: 0.5-1.0 μg/mL. ELISA: 0.1-0.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP / beta Amyloid

Background: Name/Gene ID: APP
Family: Amyloid precursor protein

Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II

Gene ID: 351

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour