JUP antibody (AA 45-114)

Catalog No. ABIN200365

This Mouse Monoclonal antibody specifically detects JUP in WB, IF and IP. It exhibits reactivity toward Human.

Quick Overview for JUP antibody (AA 45-114) (ABIN200365)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-JUP Antibody

Binding Specificity: AA 45-114

Specificity: Specific for human and mouse plakoglobin (~83kD) and does not appear to cross-react with the related b-catenin protein (~92kD). The immunoreactive epitope has been localized to a site between amino acids 45-114 of the human plakoglobin protein.

Purification: Protein A purified

Immunogen: Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.

Type of Immunogen: Fusion protein

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: IF (10 μg/mL), IP, WB (1 μg/mL)

Usage: Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation. Western Blot: 1 μg/mL. Immunofluorescence: 10 μg/mL. Immunoprecipitation:* 2-4 μg.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: JUP/CTNNG/Junction Plakoglobin

Background: Name/Gene ID: JUP
Family: Catenin

Synonyms: JUP, Desmoplakin-3, CTNNG, DPIII, Gamma catenin, Junction plakoglobin, PKGB, ARVD12, Catenin gamma, Desmoplakin III, DP3, PDGB

Gene ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location