Caspase 1 antibody (AA 206-220)

Catalog No. ABIN200371

Product Details anti-Caspase 1 Antibody

Target: Caspase 1 (CASP1)

Binding Specificity: AA 206-220

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Specificity: Recognizes an epitope within the p20 fragment of mouse caspase-1. Detects a band of ~45kD by Western blot. Does not cross-react with mouse caspase-11 or -12.

Predicted Reactivity: Percent identity by BLAST analysis: Mouse (100%) Rat (87%).

Purification: Protein G purified

Immunogen: P20 fragment of mouse caspase-1 and synthetic peptide corresponding to aa 206-220 (TALEMVKEVKEFAAC) of mouse caspase-1. Percent identity by BLAST analysis: Mouse (100%), Rat (87%).

Type of Immunogen: Synthetic peptide

Clone: 1H11

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo, WB

Usage: Suitable for use in Flow Cytometry, ELISA and Western Blot.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1 / Caspase 1 (CASP1 Products)

Background: Name/Gene ID: CASP1
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP1, Caspase-1, CASP-1, CASP1 nirs variant 1, Caspase 1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BCE, p45, IL1B-convertase, Interleukin-1 beta convertase

Gene ID: 834

UniProt: P29466

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome