Huntingtin antibody (AA 1844-2131)
Quick Overview for Huntingtin antibody (AA 1844-2131) (ABIN201061)
Target
See all Huntingtin (HTT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1844-2131
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Specificity
- Reacts with an epitope corresponding to the HDB region (amino acids 1844-2131) of the huntingtin protein. Clone 3H2240 detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. The combined use of clone 3H2240, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain.
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Purification
- Purified
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Immunogen
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Recombinant protein corresponding to amino acids 1844 - 2131 of huntingtin.
Type of Immunogen: Recombinant protein -
Isotype
- IgG1
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Application Notes
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Approved: IHC, IHC-Fr, IP, WB
Usage: Immunohistochemistry (frozen). Immunoprecipitation. Western Blot. Tested in IHC with frozen, acetone fixed rabbit brain. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.1 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Huntingtin (HTT)
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Alternative Name
- HTT / Huntingtin
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Background
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Name/Gene ID: HTT
Family: Hungtintin
Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein -
Gene ID
- 3064
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UniProt
- P42858
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Pathways
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Target
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