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Huntingtin antibody (AA 1844-2131)

This Mouse Monoclonal antibody specifically detects Huntingtin in IHC, WB, IP and IHC (fro). It exhibits reactivity toward Rabbit.
Catalog No. ABIN201061

Quick Overview for Huntingtin antibody (AA 1844-2131) (ABIN201061)

Target

See all Huntingtin (HTT) Antibodies
Huntingtin (HTT)

Reactivity

  • 64
  • 49
  • 42
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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Rabbit

Host

  • 61
  • 23
  • 2
Mouse

Clonality

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  • 33
Monoclonal

Conjugate

  • 65
  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Huntingtin antibody is un-conjugated

Application

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  • 19
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  • 8
  • 8
  • 4
  • 2
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  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

    • 15
    • 6
    • 4
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    AA 1844-2131

    Specificity

    Reacts with an epitope corresponding to the HDB region (amino acids 1844-2131) of the huntingtin protein. Clone 3H2240 detects a 350kD band on western blots but also detects smaller degradation products of huntingtin. The combined use of clone 3H2240, HDC8A4 and HDA3E10 demonstrate that huntingtin is enriched in neuronal cells in the brain.

    Purification

    Purified

    Immunogen

    Recombinant protein corresponding to amino acids 1844 - 2131 of huntingtin.

    Type of Immunogen: Recombinant protein

    Isotype

    IgG1
  • Application Notes

    Approved: IHC, IHC-Fr, IP, WB

    Usage: Immunohistochemistry (frozen). Immunoprecipitation. Western Blot. Tested in IHC with frozen, acetone fixed rabbit brain.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    0.1 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    Huntingtin (HTT)

    Alternative Name

    HTT / Huntingtin

    Background

    Name/Gene ID: HTT
    Family: Hungtintin

    Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein

    Gene ID

    3064

    UniProt

    P42858

    Pathways

    PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
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