APEX1 antibody (AA 21-70)

Catalog No. ABIN202227

This anti-APEX1 antibody is a Rabbit Polyclonal antibody detecting APEX1 in WB. Suitable for Human, Mouse, Cow, Pig, Rabbit, Horse, Monkey and Bat.

Quick Overview for APEX1 antibody (AA 21-70) (ABIN202227)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human, Mouse, Cow, Pig, Rabbit, Horse, Monkey, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APEX1 Antibody

Binding Specificity: AA 21-70

Specificity: Mouse APEX1 / APE1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Mouse, Bovine, Pig (100%) Rat, Dog, Goat (92%).

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa21-70 of mouse APEX1 (Q544Z7, NP_033817). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Panda, Bovine, Bat, Rabbit, Horse, Pig (100%), Rat, Goat, Elephant, Dog, Opossum, Guinea pig (92%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (2.5 μg/mL)

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APEX1 / APE1

Background: Name/Gene ID: APEX1

Synonyms: APEX1, AP endonuclease class I, AP lyase, APE, APE-1, APEN, APE1, APEX nuclease, Redox factor-1, AP endonuclease 1, APEX, APX, Protein REF-1, REF-1, REF1

Gene ID: 328

NCBI Accession: NP_033817

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus