APEX1 antibody (AA 79-128)

Catalog No. ABIN202230

This anti-APEX1 antibody is a Rabbit Polyclonal antibody detecting APEX1 in WB, IHC and IHC (p). Suitable for Human, Pig, Horse, Goat and Bat.

Quick Overview for APEX1 antibody (AA 79-128) (ABIN202230)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human, Pig, Horse, Goat, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-APEX1 Antibody

Binding Specificity: AA 79-128

Specificity: Human APEX1 / APE1

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Rat, Dog (92%) Bovine (91%) Pig (84%) Goat (83%).

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa79-128 of human APEX1 (P27695, NP_542379). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Bat, Horse (100%), Gorilla, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Rabbit (92%), Bovine (91%), Hamster, Pig, Guinea pig (84%), Goat (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, WB (1.25 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APEX1 / APE1

Background: Name/Gene ID: APEX1

Synonyms: APEX1, AP endonuclease class I, AP lyase, APE, APE-1, APEN, APE1, APEX nuclease, Redox factor-1, AP endonuclease 1, APEX, APX, Protein REF-1, REF-1, REF1

Gene ID: 328

NCBI Accession: NP_542379

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus