APEX1 antibody (AA 79-128)

Catalog No. ABIN202230

The Rabbit Polyclonal anti-APEX1 antibody (ABIN202230) specifically detects APEX1 in WB, IHC and IHC (p). The antibody is reactive with Human, Pig, Horse, Goat and Bat samples.

Quick Overview for APEX1 antibody (AA 79-128) (ABIN202230)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reactivity: Human, Pig, Horse, Goat, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APEX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-APEX1 Antibody

Binding Specificity: AA 79-128

Specificity: Human APEX1 / APE1

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Rat, Dog (92%) Bovine (91%) Pig (84%) Goat (83%).

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa79-128 of human APEX1 (P27695, NP_542379). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Bat, Horse (100%), Gorilla, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Rabbit (92%), Bovine (91%), Hamster, Pig, Guinea pig (84%), Goat (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, WB (1.25 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Alternative Name: APEX1 / APE1

Background: Name/Gene ID: APEX1

Synonyms: APEX1, AP endonuclease class I, AP lyase, APE, APE-1, APEN, APE1, APEX nuclease, Redox factor-1, AP endonuclease 1, APEX, APX, Protein REF-1, REF-1, REF1

Gene ID: 328

NCBI Accession: NP_542379

UniProt: P27695

Pathways: DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus