GRIN1/NMDAR1 antibody (Intracellular)

Catalog No. ABIN204490

This Mouse Monoclonal antibody specifically detects GRIN1/NMDAR1 in WB, IHC, ELISA and IHC (fro). It exhibits reactivity toward Human, Rat, Mouse and Monkey.

Quick Overview for GRIN1/NMDAR1 antibody (Intracellular) (ABIN204490)

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Reactivity: Human, Rat, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIN1/NMDAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 54-1

Product Details anti-GRIN1/NMDAR1 Antibody

Binding Specificity: Intracellular

Specificity: Recognizes human NMDAR1 (~103kD). Does not cross-react with other NMDA receptor proteins. Species cross-reactivity: mouse, rat and monkey.

Purification: Protein A purified

Immunogen: Fusion protein containing sequence from the intracellular loop between transmembrane regions III and IV of NMDAR1.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA (0.1 - 1 μg/mL), IHC, IHC-Fr, WB (1 - 5 μg/mL)

Usage: Suitable for use in ELISA, Western Blot and Immunohistochemistry. ELISA: 0.1-1 μg/mL. Western Blot: 1-5 μg/mL. Immunohistochemistry (frozen): 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for GRIN1/NMDAR1

Target: GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))

Alternative Name: GRIN1 / NMDAR1

Background: Name/Gene ID: GRIN1
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1

Gene ID: 2902

UniProt: Q05586

Pathways: Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity