CD4 antibody (FITC)

Catalog No. ABIN7472922

This anti-CD4 antibody is a Mouse Monoclonal antibody detecting CD4 in FACS. Suitable for Human.

Quick Overview for CD4 antibody (FITC) (ABIN7472922)

Target: CD4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-CD4 Antibody (FITC)

Specificity: Recognizes human CD4, a 55kD cell surface glycoprotein that is primarily expressed on a subpopulation of T lymphocytes, on peripheral blood monocytes and on tissue macrophages. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognize an epitope within domain 1, of the extracellular region, of the CD4 Molecule. Has been reported to block gp120-CD4 interaction and inhibit syncytium formation, see Piatier-Tonneau et al, 1997 for details.

Purification: Protein G purified

Immunogen: Human PHA blasts.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1 - 1:10)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: Name/Gene ID: CD4

Synonyms: CD4, CD4 antigen, CD4 receptor, CD4mut, CD4 antigen (p55), CD4 Molecule

Gene ID: 920

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events