C3AR1 antibody

Catalog No. ABIN206603

The Mouse Monoclonal anti-C3AR1 antibody is suitable to detect C3AR1 in samples from Human. It has been validated for FACS, IHC and IHC (fro).

Quick Overview for C3AR1 antibody (ABIN206603)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-C3AR1 Antibody

Specificity: Recognizes the receptor for human complement component C3a (C3aR), a 55kD cell surface protein of the rhodopsin family of G protein-coupled seven-transmembrane receptors. C3a is an anaphylatoxin, which is a potent proinflammatory mediator that possesses immunoregulatory properties. C3a regulates inflammatory functions by binding to the C3a receptor. C3aR is expressed on various tissues and leucocytes including basophils, neutrophils, mast cells, eosinophils and activated T lymphocytes. Expression levels of C3aR on human cells varies significantly between donors.

Purification: Protein G purified

Immunogen: Recombinant human C3aR protein.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:10 - 1:20), IHC, IHC-Fr

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3AR / C3a Receptor

Background: Name/Gene ID: C3AR1
Subfamily: Anaphylatoxin
Family: GPCR

Synonyms: C3AR1, AZ3B, C3AR, C3R1, C3a receptor, C3a-R, HNFAG09, Anaphylatoxin c3a receptor, C3a anaphylatoxin receptor

Gene ID: 719

Pathways: Complement System