ITGB1 antibody

Catalog No. ABIN206954

The Mouse Monoclonal anti-ITGB1 antibody is suitable to detect ITGB1 in samples from Human and Dog. It has been validated for WB, FACS and IP.

Quick Overview for ITGB1 antibody (ABIN206954)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: MEM-101A

Product Details anti-ITGB1 Antibody

Specificity: Reacts with CD29 (integrin beta1 chain), a 130 kD single chain type I glycoprotein expressed as a heterodimer (non-covalently associated with the integrin alpha subunits 1-6). CD29 is broadly expressed on majority of hematopoietic and non-hematopoietic cells (leukocytes, platelets, fibroblasts, endothelial cells, epithelial cells and mast cells).

Purification: Protein A purified

Immunogen: Raji Burkitt's lymphoma cell line.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (2 μg/mL), IP (2 μg/mL), WB (2 μg/mL)

Usage: Flow Cytometry: Recommended dilution - 2 μg/mL. Western Blotting: Recommended dilution - 2 μg/mL. Positive control - JURKAT human leukemia T-cell lysate. Kg-1a human leukemia cell lysate. Sample preparation:buffer with laurylmaltoside, 2 x non-reducing SD

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: ITGB1 / Integrin Beta 1 / CD29

Background: Name/Gene ID: ITGB1
Family: Integrin

Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta

Gene ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome