CDK6 antibody

Catalog No. ABIN208232

The Mouse Monoclonal anti-CDK6 antibody has been validated for WB, IHC, IHC (p), IP and IHC (fro). It is suitable to detect CDK6 in samples from Human.

Quick Overview for CDK6 antibody (ABIN208232)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDK6 Antibody

Specificity: Antigen Recognized in Species Human. Reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining found in head and neck tumors.

Purification: Protein A purified

Immunogen: Human recombinant full-length cdk6 polypeptide.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr, IHC-P, IP, WB

Usage: Suitable for use in Immunohistochemistry (frozen sections and for paraffin-embedded tissue after microwave treatment), Western Blot and Immunoprecipitation. Immunohistochemistry: 1:10, Incubation Time 1-4 hr at RT or overnight at 2-8?C.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile ddH2O

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.5 % BSA, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Alternative Name: CDK6

Background: Name/Gene ID: CDK6
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK6, CDKN6, Cell division protein kinase 6, Cyclin-dependent kinase 6, Crk2, PLSTIRE

Gene ID: 1021

UniProt: Q00534

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases