Dopamine d2 Receptor antibody (3rd Cytoplasmic Domain)
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- Target See all Dopamine d2 Receptor (DRD2) Antibodies
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
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Binding Specificity
- 3rd Cytoplasmic Domain
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Reactivity
- Human, Rat, Mouse, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dopamine d2 Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Specificity
- Specific for Dopamine Receptor D2 short and long form. Species cross-reactivity: Monkey, mouse and rat.
- Purification
- Affinity purified
- Immunogen
- A 28 amino acid peptide sequence from the human D2 receptor within the cytoplasmic loop #3. The immunogen peptide shows no significant homology with other dopamine receptors (D1 and D3-D5). Species sequence Homology: Bovine, canine - 100%, Xenopus - 50%.
- Isotype
- IgG
- Top Product
- Discover our top product DRD2 Primary Antibody
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- Application Notes
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Approved: ELISA (0.5 - 1 μg/mL), IHC, IP (1 - 10 μg/mL), WB (1:1000)
Usage: Suitable for use in Western Blot, Immunohistochemistry, Immunoprecipitation and ELISA. Western Blot: 1:1000. Detected Dopamine Receptor D2 on 10 μg of human brain lysates. Immunohistochemistry (Paraformaldehyde fixed sections): 2-10 μg/mL. Immunoprecipitation: 1-10 μg/mL. Using 100-400 μg of protein. An antibody made to this epitope has been shown to immunoprecipitate both the long and short forms. ELISA: 0.5-1.0 μg/mL. Positive control: Monkey brain tissue, rat brain lysate. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 % BSA.
- Handling Advice
- avoid freeze thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- Target
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
- Alternative Name
- DRD2 / Dopamine Receptor D2 (DRD2 Products)
- Synonyms
- D2DR antibody, D2R antibody, drd2b antibody, d2r2 antibody, Drd-2 antibody, d2dr antibody, d2r antibody, drd2 antibody, drd2-B antibody, DRD2 antibody, D2 antibody, CG18741 antibody, CG7569 antibody, DAMB antibody, DDR2 antibody, DOPR2 antibody, DOPR99B antibody, Dar2 antibody, Dmel\\CG18741 antibody, DopD1 antibody, DopR99B antibody, DopRII antibody, dopamine receptor D2 antibody, dopamine receptor D2 like antibody, dopamine receptor D2 L homeolog antibody, dopamine receptor D2 S homeolog antibody, Dopamine 1-like receptor 2 antibody, DRD2 antibody, drd2l antibody, drd2 antibody, Drd2 antibody, drd2.L antibody, drd2.S antibody, Dop1R2 antibody
- Background
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Name/Gene ID: DRD2
Subfamily: Dopamine
Family: GPCR
Synonyms: DRD2, D2 dopamine receptor, D2R, Dopamine receptor D2 isoform, Dopamine 2 receptor, D(2) dopamine receptor, D2DR, Dopamine D2 receptor, Dopamine receptor D2 - Gene ID
- 1813
- UniProt
- P14416
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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