LPCAT2 antibody (AA 131-230)

Catalog No. ABIN2177389

Product Details anti-LPCAT2 Antibody

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Binding Specificity: AA 131-230

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPCAT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPCAT2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LPCAT2

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Alternative Name: LPCAT2 (LPCAT2 Products)

Synonyms: AYTL1 antibody, LysoPAFAT antibody, A330042H22 antibody, Aytl1 antibody, Aytl1a antibody, lpafat1 antibody, aytl1 antibody, zgc:112165 antibody, LPCAT-2 antibody, RGD1563994 antibody, lysophosphatidylcholine acyltransferase 2 antibody, Lysophosphatidylcholine acyltransferase 2 antibody, LPCAT2 antibody, Lpcat2 antibody, lpcat2 antibody, pcat2 antibody

Background:

Synonyms: AYTL1, LysoPAFAT, Lysophosphatidylcholine acyltransferase 2, LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-AGP acyltransferase 11, 1-AGPAT 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, Acyltransferase-like 1, Lysophosphatidic acid acyltransferase alpha, LPAAT-alpha, LPCAT2, AGPAT11

Background: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.

Gene ID: 54947

UniProt: Q7L5N7