LPCAT2 antibody (N-Term)

Catalog No. ABIN6258429

Product Details anti-LPCAT2 Antibody

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPCAT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: LPCAT2 Antibody detects endogenous levels of total LPCAT2.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human LPCAT2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for LPCAT2

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Alternative Name: LPCAT2 (LPCAT2 Products)

Synonyms: AYTL1 antibody, LysoPAFAT antibody, A330042H22 antibody, Aytl1 antibody, Aytl1a antibody, lpafat1 antibody, aytl1 antibody, zgc:112165 antibody, LPCAT-2 antibody, RGD1563994 antibody, lysophosphatidylcholine acyltransferase 2 antibody, Lysophosphatidylcholine acyltransferase 2 antibody, LPCAT2 antibody, Lpcat2 antibody, lpcat2 antibody, pcat2 antibody

Background:

Description: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.

Gene: LPCAT2

Molecular Weight: 50 kDa

Gene ID: 54947

UniProt: Q7L5N7