LPCAT2 antibody (AA 131-230) (HRP)

Catalog No. ABIN2177400

This anti-LPCAT2 antibody is a Rabbit Polyclonal antibody detecting LPCAT2 in WB, ELISA, IHC (fro) and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for LPCAT2 antibody (AA 131-230) (HRP) (ABIN2177400)

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPCAT2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LPCAT2 Antibody (HRP)

Binding Specificity: AA 131-230

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPCAT2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LPCAT2

Target: LPCAT2 (Lysophosphatidylcholine Acyltransferase 2 (LPCAT2))

Alternative Name: LPCAT2

Background:

Synonyms: AYTL1, LysoPAFAT, Lysophosphatidylcholine acyltransferase 2, LPC acyltransferase 2, LPCAT-2, LysoPC acyltransferase 2, 1-acylglycerol-3-phosphate O-acyltransferase 11, 1-AGP acyltransferase 11, 1-AGPAT 11, 1-acylglycerophosphocholine O-acyltransferase, 1-alkylglycerophosphocholine O-acetyltransferase, Acetyl-CoA:lyso-platelet-activating factor acetyltransferase, Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, Acyltransferase-like 1, Lysophosphatidic acid acyltransferase alpha, LPAAT-alpha, LPCAT2, AGPAT11

Background: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.

Gene ID: 54947

UniProt: Q7L5N7