STAT5B antibody (pSer731) (PE)

Catalog No. ABIN2179494

This anti-STAT5B antibody is a Rabbit Polyclonal antibody detecting STAT5B in WB and FACS. Suitable for Human and Cow.

Quick Overview for STAT5B antibody (pSer731) (PE) (ABIN2179494)

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAT5B antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-STAT5B Antibody (PE)

Binding Specificity: pSer731

Cross-Reactivity: Cow, Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human STAT5b around the phosphorylation site of Ser731

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for STAT5B

Target: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Alternative Name: STAT5b

Background:

Synonyms: STAT5bphospho S731, Transcription factor STAT5B, Signal transducer and activator of transcription 5B, STA5B_HUMAN, STAT5, Stat5b.

Background: Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.

Gene ID: 6777

Pathways: JAK-STAT Signaling, RTK Signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation