TYK2 antibody (pTyr1054, Tyr1055)

Catalog No. ABIN218824

This Rabbit Polyclonal antibody specifically detects TYK2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TYK2 antibody (pTyr1054, Tyr1055) (ABIN218824)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TYK2 Antibody

Binding Specificity: pTyr1054, Tyr1055

Specificity: Recognizes endogenous levels of human Tyk2 only when activated by phosphorylation at tyrosine1054/1055. Does not detect other sites of tyrosine phosphorylation on Tyk2. Species sequence homology: mouse and rat-100 % .

Purification: Protein A purified

Immunogen: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding tyrosine 1054/1055 of human Tyk2. Molecular weight: 140kD.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA, WB (1:1000)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Alternative Name: TYK2

Background: Name/Gene ID: TYK2
Subfamily: TYK2/JAK
Family: Protein Kinase

Synonyms: TYK2, Tyrosine kinase 2, JTK1

Molecular Weight: 140kDa

Gene ID: 7297

UniProt: P29597

Pathways: JAK-STAT Signaling, Hepatitis C