C5 antibody

Catalog No. ABIN2191951

This Mouse Monoclonal antibody specifically detects C5 in WB and IA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for C5 antibody (ABIN2191951)

Target: C5 (Complement Component 5 (C5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoassay (IA)

Clone: 568

Product Details anti-C5 Antibody

Sterility: 0.2 μm filtered

Application Details

Application Notes: It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Restrictions: For Research Use only

Handling

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Expiry Date: 12 months

References for anti-C5 antibody (ABIN2191951)

Mollnes, Klos, Tschopp: "Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex." in: Scandinavian journal of immunology, Vol. 28, Issue 3, pp. 307-12, (1988) (PubMed).

Target Details for C5

Target: C5 (Complement Component 5 (C5))

Alternative Name: c5/c5b

Background: Monoclonal antibody 568 reacts with an epitope on C5 and on C5b. C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.

Pathways: Complement System, Carbohydrate Homeostasis