DPP4 antibody

Catalog No. ABIN2192110

This Mouse Monoclonal antibody specifically detects DPP4 in WB, IP, IHC (fro) and IA. It exhibits reactivity toward Rat and has been mentioned in 3+ publications.

Quick Overview for DPP4 antibody (ABIN2192110)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)

Clone: 5E8

Product Details anti-DPP4 Antibody

Sterility: 0.2 μm filtered

Application Details

Application Notes: For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Restrictions: For Research Use only

Handling

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Expiry Date: 12 months

References for anti-DPP4 antibody (ABIN2192110)

Ariyoshi, Mizuno, Morisue, Shimada, Fujita, Nasu, Okada, Shimomura, Yamamoto, Tsuji: "Identification of a target antigen recognized by a mouse monoclonal antibody to the bile canalicular surface of rat hepatocytes with a random phage display library." in: Acta medica Okayama, Vol. 56, Issue 4, pp. 187-91, (2002) (PubMed).

Hyodo, Mizuno, Yamada, Tsuji: "Distribution of asialoglycoprotein receptor in human hepatocellular carcinoma." in: Liver, Vol. 13, Issue 2, pp. 80-5, (1993) (PubMed).

Mizuno, Yamada, Sugiyama, Vierling, Brown: "Monoclonal antibodies identifying antigens on distinct domains of rat hepatocytes." in: Liver, Vol. 7, Issue 5, pp. 251-9, (1988) (PubMed).

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Background: Dipeptidyl peptidase IV (DPP IV) is widely distributed in a number of mammalian tissues and is suggested to play an important role in various kinds of biological processes. DPP IV (CD26) is a serine-type protease that removes the amino-terminal dipeptide from peptide substrate provided that the penultimate amino acid residue is proline or alanine. DPP IV plays an important role in the reclamation of peptide nitrogen from larger peptides. The monoclonal antibody 5E8 reacts with DPP IV present on the apical surface of epithelial cells in the pancreas, small intestine, colon, and bile duct. Furthermore antibody 5E8 reacts with DPP IV on the laminar portions of the proximal renal tubule cells, and, weakly, on the glomeruli.

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity