CHEK2 antibody (pThr68)
Quick Overview for CHEK2 antibody (pThr68) (ABIN219984)
Target
See all CHEK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- pThr68
-
Specificity
- Recognizes endogenous levels of human Chk2 only when phosphorylated at threonine 68 (62kD). Does not cross-react with Chk2 phosphorylated at other sites. Species cross-reactivity: Monkey.
-
Purification
- Protein A purified
-
Immunogen
-
Synthetic phosphopeptide corresponding to residues surrounding Thr68 of human Chk2 (KLH coupled).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
-
-
-
-
Application Notes
-
Approved: ELISA, Flo (1:25), ICC (1:100), IF, IP (1:200), WB (1:1000)
Usage: Suitable for use in ELISA, Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Flow Cytometry. Western Blot: 1:1000. Immunocytochemistry: 1:100. Immunoprecipitation: 1:200. Flow Cytometry: 1:25. -
Comment
-
Target Species of Antibody: Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.
-
Preservative
- Without preservative
-
Handling Advice
- Avoid repeat freeze-thaw cycles.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
-
-
- CHEK2 (Checkpoint Kinase 2 (CHEK2))
-
Alternative Name
- CHEK2 / CHK2
-
Background
-
Name/Gene ID: CHEK2
Subfamily: CDS1
Family: Protein Kinase
Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425 -
Gene ID
- 11200
-
UniProt
- O96017
-
Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
Target
-