CHEK2 antibody (pSer33, Ser35)
Quick Overview for CHEK2 antibody (pSer33, Ser35) (ABIN219992)
Target
See all CHEK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer33, Ser35
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Specificity
- Detects endogenous levels of Chk2 only when phosphorylated at Ser33/35. The antibody does not cross-react with Chk2 phosphorylated at other sites.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser33/35 of human Chk2.
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: WB (1:1000)
Usage: Suitable for use in Western Blot.
Not recommended for: IHC-P -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- CHEK2 (Checkpoint Kinase 2 (CHEK2))
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Alternative Name
- CHEK2 / CHK2
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Background
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Name/Gene ID: CHEK2
Subfamily: CDS1
Family: Protein Kinase
Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425 -
Gene ID
- 11200
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UniProt
- O96017
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Pathways
- p53 Signaling, Apoptosis, Cell Division Cycle
Target
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