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CHEK2 antibody (pSer33, Ser35)

The Rabbit Polyclonal anti-CHEK2 antibody has been validated for WB. It is suitable to detect CHEK2 in samples from Human.
Catalog No. ABIN219992

Quick Overview for CHEK2 antibody (pSer33, Ser35) (ABIN219992)

Target

See all CHEK2 Antibodies
CHEK2 (Checkpoint Kinase 2 (CHEK2))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This CHEK2 antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    pSer33, Ser35

    Specificity

    Detects endogenous levels of Chk2 only when phosphorylated at Ser33/35. The antibody does not cross-react with Chk2 phosphorylated at other sites.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser33/35 of human Chk2.

    Type of Immunogen: Synthetic phospho-peptide

    Isotype

    IgG
  • Application Notes

    Approved: WB (1:1000)

    Usage: Suitable for use in Western Blot.

    Not recommended for: IHC-P

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target

    CHEK2 (Checkpoint Kinase 2 (CHEK2))

    Alternative Name

    CHEK2 / CHK2

    Background

    Name/Gene ID: CHEK2
    Subfamily: CDS1
    Family: Protein Kinase

    Synonyms: CHEK2, BA444G7, Cds1 homolog, Checkpoint kinase 2, Checkpoint-like protein CHK2, CHK2 checkpoint homolog, CHK2, HCds1, LFS2, RAD53, Rad53 homolog, HCHK2, HuCds1, PP1425

    Gene ID

    11200

    UniProt

    O96017

    Pathways

    p53 Signaling, Apoptosis, Cell Division Cycle
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