MSK1 antibody (pSer376)

Catalog No. ABIN220561

This Rabbit Polyclonal antibody specifically detects MSK1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MSK1 antibody (pSer376) (ABIN220561)

Target: MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MSK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MSK1 Antibody

Binding Specificity: pSer376

Specificity: Detects endogenous MSK1 only when phosphorylated at Ser376. Does not recognize MSK1 phosphorylated at other sites, nor does it recognize phosphorylated RSK1, RSK2 or RSK3. Species cross-reactivity: Human, mouse, and rat.

Purification: Protein A purified

Immunogen: Synthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser376 of human MSK1.

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol. No preservative added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MSK1

Target: MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))

Alternative Name: RPS6KA5 / MSK1

Background: Name/Gene ID: RPS6KA5
Subfamily: MSK
Family: Protein Kinase

Synonyms: RPS6KA5, MSPK1, RLPK, MSK1, RSK-like protein kinase, RSKL, S6K-alpha-5

Gene ID: 9252

UniProt: O75582

Pathways: MAPK Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades