Tuberin antibody (pTyr1571)

Catalog No. ABIN221058

This anti-Tuberin antibody is a Rabbit Polyclonal antibody detecting Tuberin in WB. Suitable for Human.

Quick Overview for Tuberin antibody (pTyr1571) (ABIN221058)

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tuberin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tuberin Antibody

Binding Specificity: pTyr1571

Specificity: Detects endogenous levels of tuberin only when phosphorylated at Tyr1571 (Mr 200kD). Does not detect tuberin phosphorylated at other sites. Species cross-reactivity: Human, mouse and monkey.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide corresponding to residues around Tyr1571 of human tuberin (KLH coupled).

Type of Immunogen: Synthetic phospho-peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2. No preservative added, no stabilizing proteins added.

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Tuberin

Target: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Alternative Name: Tuberin / TSC2

Background: Name/Gene ID: TSC2

Synonyms: TSC2, LAM, Tuberous sclerosis 2 protein, TSC4, Tuberin, Tuberous sclerosis 2

Gene ID: 7249

UniProt: P49815

Pathways: RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus