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Tyrosine Hydroxylase antibody (pSer40)

This Rabbit Polyclonal antibody specifically detects Tyrosine Hydroxylase in WB and IP. It exhibits reactivity toward Rat.
Catalog No. ABIN222754

Quick Overview for Tyrosine Hydroxylase antibody (pSer40) (ABIN222754)

Target

See all Tyrosine Hydroxylase (TH) Antibodies
Tyrosine Hydroxylase (TH)

Reactivity

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Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Tyrosine Hydroxylase antibody is un-conjugated

Application

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Western Blotting (WB), Immunoprecipitation (IP)
  • Binding Specificity

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    pSer40

    Specificity

    Tyrosine Hydroxylase, phosphoSer40. The antibody recognizes a protein of 60kD corresponding to TH phosphorylated at Ser40. Depending on brain region being studied, protein loads and detection methods used some higher molecular weight bands may be detected. Species cross-reactivity: Rat.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic peptide from the phosphoSer40 of rat Tyrosine Hydroxylase.

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Application Notes

    Approved: IP, WB

    Usage: Suitable for use in Western Blot, Immunoprecipitation.

    Comment

    Target Species of Antibody: Rat

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Dulbeccos PBS (divalent-deficient), 10 mM HEPES,  pH 7.2, 20 mM Tris-HCl,  pH 7.6, 1 mg/mL BSA, 0.1 % PVP-40, 0.05 % Tween 20, 0.1 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short term: 4°C
    Long term: Add glycerol (40-50%) -20°C.
  • Target

    Tyrosine Hydroxylase (TH)

    Alternative Name

    TH / Tyrosine Hydroxylase

    Background

    Name/Gene ID: TH
    Family: Monooxygenase

    Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

    Gene ID

    7054

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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