Tyrosine Hydroxylase antibody (pSer40)
Quick Overview for Tyrosine Hydroxylase antibody (pSer40) (ABIN222754)
Target
See all Tyrosine Hydroxylase (TH) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer40
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Specificity
- Tyrosine Hydroxylase, phosphoSer40. The antibody recognizes a protein of 60kD corresponding to TH phosphorylated at Ser40. Depending on brain region being studied, protein loads and detection methods used some higher molecular weight bands may be detected. Species cross-reactivity: Rat.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic peptide from the phosphoSer40 of rat Tyrosine Hydroxylase.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: IP, WB
Usage: Suitable for use in Western Blot, Immunoprecipitation. -
Comment
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Target Species of Antibody: Rat
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Dulbeccos PBS (divalent-deficient), 10 mM HEPES, pH 7.2, 20 mM Tris-HCl, pH 7.6, 1 mg/mL BSA, 0.1 % PVP-40, 0.05 % Tween 20, 0.1 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
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- Tyrosine Hydroxylase (TH)
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Alternative Name
- TH / Tyrosine Hydroxylase
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Background
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Name/Gene ID: TH
Family: Monooxygenase
Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase -
Gene ID
- 7054
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UniProt
- P07101
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Pathways
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
Target
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