NGFR antibody

Catalog No. ABIN224778

This anti-NGFR antibody is a Mouse Monoclonal antibody detecting NGFR in WB, IHC, IP, IHC (fro) and Func. Suitable for Rat.

Quick Overview for NGFR antibody (ABIN224778)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Product Details anti-NGFR Antibody

Specificity: Specific for the rat low affinity Nerve Growth Factor-Receptor (p75).

Purification: Ion exchange chromatography

Immunogen: Rat p75, low affinity NGF receptor.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Func, IHC, IHC-Fr, IP (5 μg/mL), WB (1 - 5 μg/mL)

Usage: Suitable for use in Immunohistochemistry (frozen), Immunoprecipitation, Western Blot and Inhibition of NGF binding. Immunohistochemistry (frozen): 1-5 μg/mL on rat. Western Blot: 1-5 μg/mL (Non-reducing conditions only). Immunoprecipitation: 5 μg/mL, 0.5 % Triton X-100 buffer, PC12 positive control.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Alternative Name: NGFR / CD271 / p75

Background: Name/Gene ID: NGFR
Family: TNF Receptor

Synonyms: NGFR, CD271, CD271 antigen, gp80-LNGFR, Nerve growth factor receptor, p75 ICD, p75(NTR), p75NTR, TNFR superfamily, member 16, NGF receptor, TNFRSF16

Gene ID: 4804

UniProt: P08138

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding