Progesterone Receptor antibody (pSer294)

Catalog No. ABIN227372

The Mouse Monoclonal anti-Progesterone Receptor antibody is suitable to detect Progesterone Receptor in samples from Human, Rat and Mouse. It has been validated for WB and IHC.

Quick Overview for Progesterone Receptor antibody (pSer294) (ABIN227372)

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: pSer294

Specificity: Specific for the ~90k PR-A isoform and the ~120k PR-B isoform phosphorylated at Ser294. Immunolabeling is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide

Purification: Protein G purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer24 of human progesterone receptor.

Isotype: IgG1

Application Details

Application Notes: Approved: IHC (1:1000), WB (1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR/PR/Progesterone Receptor

Background: Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: PGR, NR3C3, PR, Progesterone receptor

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration