FGFR1 antibody (pTyr653, Tyr654)

Catalog No. ABIN228105

This anti-FGFR1 antibody is a Rabbit Polyclonal antibody detecting FGFR1 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for FGFR1 antibody (pTyr653, Tyr654) (ABIN228105)

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FGFR1 Antibody

Binding Specificity: pTyr653, Tyr654

Specificity: Detects overexpressed levels of Tyr653/654-phosphorylated FGF receptors. This antibody slightly cross-reacts with activated PDGF receptor and insulin/IGF-I receptors but does not cross-react with other tyrosine-phosphorylated proteins. Species cross-reactivity: Human, mouse and rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide (KLH coupled) corresponding to residues surrounding Tyr653/654 of human FGFR-1 (the corresponding sequences are the same in FGFR-2, -3 and -4).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Alternative Name: FGFR1

Background: Name/Gene ID: FGFR1
Subfamily: FGF Receptor
Family: Protein Kinase

Synonyms: FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD

Gene ID: 2260

UniProt: P11362

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins