Huntingtin antibody (pSer421)

Catalog No. ABIN2286907

This Rabbit Polyclonal antibody specifically detects Huntingtin in IHC, WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Huntingtin antibody (pSer421) (ABIN2286907)

Target: Huntingtin (HTT)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-Huntingtin Antibody

Binding Specificity: AA 416-424, pSer421

Sequence: R-S-R-S-G-pS-I-V-E

Cross-Reactivity: Human

Cross-Reactivity (Details): Calculated cross reactivity: Hu

Characteristics: Huntingtin Protein, phosphorylated (Ser421) (Huntington Disease)

Purification: Purified by immunoaffinity chromatography.

Immunogen: A synthetic phosphopeptide corresponding to aa416-424, R-S-R-S-G-pS-I-V-E of the human huntingtin gene protein (mutations cause Huntington's disease poly-GLU expansions causing plaques)

Isotype: IgG

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in PBS, 0.01 % sodium azide. No stabilizing proteins added.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: Huntingtin Protein

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport