Progesterone Receptor antibody (pSer190)
Quick Overview for Progesterone Receptor antibody (pSer190) (ABIN229148)
Target
See all Progesterone Receptor (PGR) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer190
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Specificity
- Detects endogenous levels of human progesterone receptor B and A forms only when phosphorylated at Ser190 and Ser26, respectively. Does not cross-react with other PR family members.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic phosphopeptide corresponding to residues surrounding Ser190 of human progesterone receptor (KLH).
Type of Immunogen: Synthetic phospho-peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA, IP (1:50), WB (1:1000)
Usage: Suitable for use in Western Blot, ELISA and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:50. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Progesterone Receptor (PGR)
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Alternative Name
- PGR/PR/Progesterone Receptor
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Background
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Name/Gene ID: PGR
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: PGR, NR3C3, PR, Progesterone receptor -
Gene ID
- 5241
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UniProt
- P06401
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Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Target
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