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GDF15 antibody (N-Term)

Name: GDF15 antibody (N-Term)
SKU: ABIN238331
Price: 485.54 USD
Availability: InStock

GDF15 Reactivity: Human FACS, cELISA Host: Mouse Monoclonal ME-6D10 unconjugated

FACS

Capillary gel electrophoresis of purified ME-1C4 monoclonal antibody. (GDF15 antibody (N-Term))

SDS

2 images

Catalog No. ABIN238331

Datasheet as PDF

Target See all GDF15 Antibodies

GDF15 (Growth Differentiation Factor 15 (GDF15))
Binding Specificity
15

12

12

7

5

5

5

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 30-194, N-Term
Reactivity
95

34

21

1

1
Human
Host
90

13

3

1
Mouse
Compatible Secondaries
Clonality
90

16

1
Monoclonal
Conjugate
57

14

9

6

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This GDF15 antibody is un-conjugated
Application
87

56

41

13

13

12

7

6

6

5

4

3

2

1
Flow Cytometry (FACS), Cell-ELISA (cELISA)

Purification

Protein G

Immunogen

genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein

Clone

ME-6D10

Isotype

IgG1

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GDF15 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal Biotin

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GDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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GDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (AA 16-143) antibody
GDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated

anti-Growth Differentiation Factor 15 (GDF15) (N-Term) antibody
GDF15 Reactivity: Human WB, ELISA, IHC, ICC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Comment

Synonyms: GDF15

Restrictions

For Research Use only
Buffer

PBS, pH 7.2

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C

Storage Comment

short term: 2 °C - 8 °C, long term: -20 °C
Target

GDF15 (Growth Differentiation Factor 15 (GDF15))

Alternative Name

MIC-1 (GDF15 Products)

Background

Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.

UniProt

Q99988

Pathways

SARS-CoV-2 Protein Interactome