RAP1GDS1 antibody

Catalog No. ABIN2443838

The Rabbit Polyclonal anti-RAP1GDS1 antibody is suitable to detect RAP1GDS1 in samples from Human. It has been validated for WB.

Quick Overview for RAP1GDS1 antibody (ABIN2443838)

Target: RAP1GDS1 (RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1GDS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAP1GDS1 Antibody

Purpose: RAP1GDS1 Rabbit Polyclonal Antibody

Specificity: The antibody recognizes the human RAP1GDS1 protein.

Application Details

Application Notes: WB 1:1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 100 μL: WB 1:1000 - 1:3000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Preservative: Without preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Expiry Date: 24 months

Target Details for RAP1GDS1

Target: RAP1GDS1 (RAP1, GTP-GDP Dissociation Stimulator 1 (RAP1GDS1))

Alternative Name: RAP1GDS1

Background:

Rap1 GTPase-GDP dissociation stimulator 1, Exchange factor smgGDS, SMG GDS protein, SMG P21 stimulatory GDP/GTP exchange protein

Small G-protein dissociation stimulator (Smg-GDS) is a guanine nucleotide exchange factor which displays a wide variety of target proteins both from the Ras and Rho families. Small GTPases are known for their ability to bind GTP and hydrolyze the bound GTP to GDP. SmgGDS has been shown to be upregulated in several types of cancer such as non-small cell lung carcinoma and prostate cancer, where it promotes both proliferation and migration.

UniProt: P52306

Pathways: SARS-CoV-2 Protein Interactome