CHGB antibody (C-Term)

Catalog No. ABIN2443940

The Rabbit Polyclonal anti-CHGB antibody is suitable to detect CHGB in samples from Human and Mammalian. It has been validated for WB.

Quick Overview for CHGB antibody (C-Term) (ABIN2443940)

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Reactivity: Human, Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHGB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHGB Antibody

Binding Specificity: AA 635-657, C-Term

Purpose: Chromogranin-B (C-term) Rabbit Polyclonal Antibody

Specificity: The antibody recognizes an epitope in C-terminal (AA 635-657) of Chromogranine-B

Immunogen: C-terminal peptide (AA 635-657)

Application Details

Application Notes: WB 1:2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 100 μL: WB 1:2000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Preservative: Without preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Expiry Date: 24 months

Target Details for CHGB

Target: CHGB (Chromogranin B (Secretogranin 1) (CHGB))

Alternative Name: Chromogranin-B

Background:

hCGB, Secretogranin I

Chromogranin-B is a prohormone and a member of the secretory granin family found in mammalian neuroendocrine cells. Although Chromogranin-B shares certain homology and binding properties with family member Chromogranin-A, the two proteins are thought to be mostly segregated in secretory granules. Chromogranin-B may be cleaved into multiple different peptides, some with identified biological activity. Recent research has indicated that Chromogranin-B may serve as a biomarker for heart failure in patients.

UniProt: P05060