Caspase 3 antibody (AA 166-183)

Catalog No. ABIN2450296

The Rabbit Polyclonal anti-Caspase 3 antibody has been validated for WB and IHC (p). It is suitable to detect Caspase 3 in samples from Human.

Quick Overview for Caspase 3 antibody (AA 166-183) (ABIN2450296)

Target: Caspase 3 (CASP3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caspase 3 Antibody

Binding Specificity: AA 166-183

Specificity: Human caspase-3 amino acids 166-183 (TELDSGIETDSGVDDDMA)1

Cross-Reactivity: Baboon, Hamster, Mouse (Murine)

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset, Rabbit (94%) Monkey, Rat, Hamster, Horse (89%) Bovine, Bat, Dog, Panda, Pig (83%).

Purification: Immunoaffinity Chromatography

Immunogen: Human caspase-3 amino acids 166-183 (TELDSGIETDSGVDDDMA).

Isotype: IgG

Application Details

Application Notes: IHC-P (10 µg/mL), WB

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: TBS, pH 7.4, 50% glycerol, 0.5 mg/mL BSA, 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for Caspase 3

Target: Caspase 3 (CASP3)

Alternative Name: CASP3 / Caspase 3

Background: Standard Gene Symbol: CASP3, Gene Family: Protease, Gene Subfamily: Cysteine C14, Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama

Gene ID: 836

UniProt: P42574

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation