SIL1 antibody

Catalog No. ABIN2458900

Product Details anti-SIL1 Antibody

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIL1.

Application Details

Application Notes: SIL1 antibody can be used for detection of SIL1 by ELISA at 1:312500. SIL1 antibody can be used for detection of SIL1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SIL1 antibody at -20 °C.

Target Details for SIL1

Target: SIL1 (Nucleotide Exchange Factor SIL1 (SIL1))

Alternative Name: SIL1 (SIL1 Products)

Synonyms: 1810057E01Rik antibody, AI042831 antibody, wz antibody, BAP antibody, MSS antibody, ULG5 antibody, endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) antibody, SIL1 nucleotide exchange factor L homeolog antibody, SIL1 nucleotide exchange factor antibody, Sil1 antibody, sil1.L antibody, SIL1 antibody

Background: SIL1 is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in its gene have been associated with Marinesco-Sjogren syndrome.This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.

Molecular Weight: 49 kDa

Gene ID: 64374

NCBI Accession: NP_001032722

UniProt: Q9H173

Pathways: Unfolded Protein Response, SARS-CoV-2 Protein Interactome