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Sep 15 antibody

SEP15 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2459187
$653.13
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all Sep 15 (SEP15) Antibodies
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Reactivity
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 10
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sep 15 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB)
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human Septin 15.
  • Application Notes
    Septin 15 antibody can be used for detection of Septin 15 by ELISA at 1:312500. Septin 15 antibody can be used for detection of Septin 15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store Septin 15 antibody at -20 °C.
  • Target
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Abstract
    SEP15 Products
    Synonyms
    9430015P09Rik antibody, cb29 antibody, zgc:86882 antibody, BcDNA:SD16138 antibody, Dmel\\CG7484 antibody, Prise 8 antibody, Sep15 antibody, selenoprotein F antibody, CG7484 gene product from transcript CG7484-RB antibody, SELENOF antibody, Selenof antibody, selenof antibody, CG7484 antibody
    Background
    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Molecular Weight
    15 kDa
    Gene ID
    9403
    NCBI Accession
    NP_004252
    UniProt
    O60613
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