COG2 antibody

Catalog No. ABIN2459814

Product Details anti-COG2 Antibody

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COG2.

Application Details

Application Notes: COG2 antibody can be used for detection of COG2 by ELISA at 1:62500. COG2 antibody can be used for detection of COG2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COG2 antibody at -20 °C.

Target Details for COG2

Target: COG2 (Conserved oligomeric Golgi complex subunit 2 (COG2))

Alternative Name: COG2 (COG2 Products)

Synonyms: zC8A9.2 antibody, zgc:56436 antibody, LDLC antibody, 1190002B08Rik antibody, 2700012E02Rik antibody, C86089 antibody, Ldlc antibody, component of oligomeric golgi complex 2 antibody, cog2 antibody, COG2 antibody, Cog2 antibody

Background: Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).

Molecular Weight: 83 kDa

Gene ID: 22796

NCBI Accession: NP_031383

UniProt: Q14746