Paired Box 3 antibody

Catalog No. ABIN2460470

The Rabbit Polyclonal anti-Paired Box 3 antibody has been validated for WB and ELISA. It is suitable to detect Paired Box 3 in samples from Human, Mouse, Rat and Dog.

Quick Overview for Paired Box 3 antibody (ABIN2460470)

Target: Paired Box 3 (PAX3)

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Paired Box 3 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.

Application Details

Application Notes: PAX3 antibody can be used for detection of PAX3 by ELISA at 1:312500. PAX3 antibody can be used for detection of PAX3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX3 antibody at -20 °C.

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background: PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.

Molecular Weight: 45 kDa

Gene ID: 5077

NCBI Accession: NP_852126

UniProt: Q86UQ3

Pathways: Sensory Perception of Sound, Tube Formation