T-Box 5 antibody

Catalog No. ABIN2460714

This anti-T-Box 5 antibody is a Rabbit Polyclonal antibody detecting T-Box 5 in WB and ELISA. Suitable for Human, Mouse, Rat, Dog and Zebrafish (Danio rerio).

Quick Overview for T-Box 5 antibody (ABIN2460714)

Target: T-Box 5 (TBX5)

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-T-Box 5 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX5.

Application Details

Application Notes: TBX5 antibody can be used for detection of TBX5 by ELISA at 1:62500. TBX5 antibody can be used for detection of TBX5 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX5 antibody at -20 °C.

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5

Background: TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX5 is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in TBX5 have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for TBX5.

Molecular Weight: 58 kDa, 60 kDa, 53 kDa, 39 kDa, 58 kDa

Gene ID: 6910

NCBI Accession: NP_000183

UniProt: Q99593