Tryptophan Hydroxylase 2 antibody

Catalog No. ABIN2460874

This Rabbit Polyclonal antibody specifically detects Tryptophan Hydroxylase 2 in WB and ELISA. It exhibits reactivity toward Human and Dog.

Quick Overview for Tryptophan Hydroxylase 2 antibody (ABIN2460874)

Target: Tryptophan Hydroxylase 2 (TPH2)

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Tryptophan Hydroxylase 2 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPH2.

Application Details

Application Notes: TPH2 antibody can be used for detection of TPH2 by ELISA at 1:62500. TPH2 antibody can be used for detection of TPH2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TPH2 antibody at -20 °C.

Target Details for Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Alternative Name: TPH2

Background: Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility.

Molecular Weight: 56 kDa

Gene ID: 121278

NCBI Accession: NP_775489

UniProt: Q8IWU9