COPS2 antibody
Quick Overview for COPS2 antibody (ABIN2460887)
Target
See all COPS2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Antibody is purified by peptide affinity chromatography method.
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Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COPS2.
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anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 344-443) antibody
COPS2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4B12 unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyCOPS2 Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-310) antibodyCOPS2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (C-Term) antibodyVerified COPS2 Reactivity: Human, Mouse WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-310) antibodyCOPS2 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (Internal Region) antibodyCOPS2 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) antibodyCOPS2 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (N-Term) antibodyCOPS2 Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Horse, Rabbit, Monkey, Guinea Pig, Pig, Chicken, Xenopus laevis, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) (AA 1-50) antibodyCOPS2 Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis WB, IHC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
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Application Notes
- COPS2 antibody can be used for detection of COPS2 by ELISA at 1:312500. COPS2 antibody can be used for detection of COPS2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store COPS2 antibody at -20 °C.
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- COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
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Alternative Name
- COPS2
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Background
- COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
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Molecular Weight
- 51 kDa
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Gene ID
- 9318
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NCBI Accession
- NP_004227
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UniProt
- P61201
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Pathways
- Cell Division Cycle
Target
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