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CREM antibody

CREM Reactivity: Human, Mouse, Rat, Dog WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2461049
  • Target See all CREM Antibodies
    CREM (CAMP Responsive Element Modulator (CREM))
    Reactivity
    • 42
    • 40
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 54
    • 3
    • 1
    Rabbit
    Clonality
    • 56
    • 1
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This CREM antibody is un-conjugated
    Application
    • 36
    • 26
    • 26
    • 20
    • 18
    • 7
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREM.
    Top Product
    Discover our top product CREM Primary Antibody
  • Application Notes
    CREM antibody can be used for detection of CREM by ELISA at 1:1562500. CREM antibody can be used for detection of CREM by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store CREM antibody at -20 °C.
  • Target
    CREM (CAMP Responsive Element Modulator (CREM))
    Alternative Name
    CREM (CREM Products)
    Synonyms
    CREM antibody, ICER antibody, CREM-2 antibody, hCREM-2 antibody, ICERI antibody, Icer antibody, cAMP responsive element modulator antibody, CREM antibody, Crem antibody
    Background
    CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.
    Molecular Weight
    13 kDa
    Gene ID
    1390
    NCBI Accession
    NP_874386
    UniProt
    O75519
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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